UI Thread?

your loop will never finish so that you can change code as follows:

 public frmmain()
        {
            InitializeComponent();
            BlackMagic swr = new BlackMagic();
            swr.OpenProcessAndThread(SProcess.GetProcessFromProcessName("Game.exe"));
            uint timeraddress = 0x00286C60;


            int[] click = new int[15] { 21750, 21916, 22083, 22166, 22250, 22416, 22583, 22749, 22833, 22916, 23000, 23083, 23249, 23416, 23500 };

            int offset = 0;
            int holdtime = 40;
            int clickcounter = 0;
            while (clickcounter <= 10)
            {

                int maptimer = swr.ReadInt(timeraddress);
                maptimerlabel.Text = "Map Time: " + maptimer;
                if (maptimer >= click[clickcounter] + offset)
                {
                    InputSimulator.SimulateKeyDown(VirtualKeyCode.VK_N);
                    Thread.Sleep(holdtime);
                    clickcounter = clickcounter + 1;
                    InputSimulator.SimulateKeyUp(VirtualKeyCode.VK_N);
                }
            }
            
           Thread thread = new Thread(new ThreadStart(ChangeMapTimerLabel));
            thread.Start();
        }
 private void ChangeMapTimerLabel()
        {
           maptimerlabel.Invoke((MethodInvoker)(() => maptimerlabel.Text = "Finished !"));
        }

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Hope above help !

Doanh