can we create Cascading drop down filtration in custom web part property?

Hi,

You will have to create a custom editorpart for this.

Please find the references below for the same.

http://www.dmcinfo.com/latest-thinking/blog/articletype/articleview/articleid/263/custom-editor-parts-in-sharepoint-2010.aspx

http://sptechbytes.blogspot.com/2013/02/sharepoint-2010-creating-custom-editor.html

Hope it helps!!!

Regards,

Sharath

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sharath kumart shivarama